Delayed Graft Function and the Risk for Death with a Functioning Graft

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Delayed Graft Function

Delayed graft function (DGF) is a common complication of renal transplantation. According to a clinical data analysis of 34,647 cases of cadaveric renal transplantation documented by the Renal Transplantation Registry of the United Network Sharing (UNOS), graft function did not recover instantly after transplantation and for ever in some cases; the 1-year rate of graft loss was up to 20% in cas...

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BuMPy road of delayed graft function.

DELAYED GRAFT FUNCTION (DGF) occurs in 20–30% of renal transplants and contributes significantly to the gradual loss of grafts through accelerated development of chronic allograft dysfunction. Members of the transforming growth factor(TGF) family are incriminated as the major driving force for developing fibrosis. In an issue of the American Journal of Physiology-Renal Physiology, Simone and co...

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Impact of delayed graft function on renal function and graft survival in deceased kidney transplantation.

OBJECTIVES To define the risk factors for delayed graft function and study the impact of such delays on renal function and long-term allograft survival in renal transplant recipients. DESIGN Single-centre retrospective study. SETTING Regional hospital, Hong Kong. PATIENTS Records of 118 Chinese renal transplant recipients from 1 July 1997 to 31 July 2005 were reviewed, and categorised int...

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Urinary reflux to the non-functioning previous renal graft

Nuclear medicine imaging is routinely used for evaluation of perfusion and function of the transplanted kidneys. At present, the radiopharmaceutical of choice for this study in our center is Tc 99m-Ec. Complications of the kidney graft are demonstrable in the early and delayed images. One of these complications is vesicoureteral reflux to the graft or to the native kidneys. We present a 27 year...

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Death with functioning graft in living donor kidney transplantation: analysis of risk factors.

BACKGROUND Death with a functioning graft (DWF) has been reported as a major cause of graft loss after renal transplantation. It has been reported to occur in 9-30%. METHODS From March 1976 to January 2002, a total of 1400 living donor renal transplants were performed in our center. Out of 257 reported deaths among our patients, 131 recipients died with functioning grafts after a mean period ...

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ژورنال

عنوان ژورنال: Journal of the American Society of Nephrology

سال: 2009

ISSN: 1046-6673,1533-3450

DOI: 10.1681/asn.2009040412